Status:
RECRUITING
TRANS-FOODS: Preventing Peanut Allergy Through Improved Understanding of the Transcutaneous Sensitisation Route, Novel Food Processing and Skin Care Adaptations
Lead Sponsor:
King's College London
Collaborating Sponsors:
University Hospital, Bonn
Institut Curie
Conditions:
Allergy;Food
Food Allergy Peanut
Eligibility:
All Genders
18-65 years
Phase:
NA
Brief Summary
This project aims to study the immune responses to peanut allergen in those with a skin barrier defect with and without skin massage, specifically it aims to: 1. Establish if peanut allergen componen...
Detailed Description
The study aims to understand how peanut processing methods and peanut co-administration with oils, as is standard during the industrial processing of peanuts, influences the development of peanut alle...
Eligibility Criteria
Inclusion
- Adult healthy volunteers (50% of the cohort), and adults with dry skin and AD (fulfilling the refined Hanifin and Rajka criteria, 50% of the cohort).
- Willingness to apply the study intervention and to not use any other topical preparations over theforearms during the study period.
Exclusion
- History of peanut allergy.
- Positive skin prick test to peanut (\>0 mm).
- No regular consumption of peanut products.
- Widespread AD, in particular if this involves the test sites of the forearms.
Key Trial Info
Start Date :
April 5 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
May 31 2025
Estimated Enrollment :
120 Patients enrolled
Trial Details
Trial ID
NCT05407012
Start Date
April 5 2024
End Date
May 31 2025
Last Update
May 6 2024
Active Locations (1)
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1
Unit for Population-Based Dermatology Research
London, United Kingdom, SE1 7EH