Status:
UNKNOWN
The Effect of Probiotics on Systemic Inflammation and Metabolic Endotoxemia in Patients Undergoing Bariatric Surgery
Lead Sponsor:
Medical University of Gdansk
Collaborating Sponsors:
Pomeranian Medical University Szczecin
Conditions:
Bariatric Surgery Candidate
Dysbiosis
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
This study explores the effects of probiotic administration on the outcomes of surgical treatment, and also on the state of the intestinal microbiota and the intestinal barrier. The study protocol is ...
Detailed Description
The study is designed as a randomized double-blind placebo-controlled clinical trial with a 12-week probiotics intervention period. Eighty patients qualified for one of 3 types of bariatric surgery Ro...
Eligibility Criteria
Inclusion
- qualification for LSG, RYGB, OAGB bariatric surgery
- age over 18
- written consent to participate in the study
Exclusion
- allergy/intolerance to any of the ingredients of the preparations,
- inflammatory bowel diseases,
- current antibiotic therapy,
- immunosuppression,
- biological treatment,
- long-term antibiotic therapy,
- taking probiotics in the 1 month prior to study enrollment,
- neurodegenerative diseases.
Key Trial Info
Start Date :
August 2 2021
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 1 2024
Estimated Enrollment :
80 Patients enrolled
Trial Details
Trial ID
NCT05407090
Start Date
August 2 2021
End Date
June 1 2024
Last Update
June 7 2022
Active Locations (1)
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1
Medical University of Gdańsk
Gdansk, Pomeranian, Poland, 80-210