Status:

COMPLETED

Effects of Energy and Physical Density Manipulation on Appetite

Lead Sponsor:

United States Army Research Institute of Environmental Medicine

Collaborating Sponsors:

US Army Research and Development Command- Soldier Center

Conditions:

Appetite

Eating Behavior

Eligibility:

All Genders

17-39 years

Phase:

NA

Brief Summary

As individuals tend to eat a constant weight or volume of food, manipulating physical and energy densities generally results in changes in energy intake without affecting subjective appetite sensation...

Detailed Description

A historical challenge for military personnel operating in austere, remote environments is the ability to pack and carry enough food to sustain their operational and nutritional needs. To address this...

Eligibility Criteria

Inclusion

  • Body mass index (BMI) ≤ 30.0 kg/m2
  • Willing to abstain from alcohol for 24 hours prior to and during days 1-2 of each study phase.
  • Willing to abstain from strenuous exercise for 24 hours prior to and during days 1-2 of each study phase.
  • Willing to abstain from a vegetarian/vegan diet or other highly restrictive diet (e.g., ketogenic diet, very high protein diet, Paleo diet) for two weeks prior to and throughout the study.
  • Willing to maintain body weight throughout study.
  • Willing to maintain usual diet (if not a restrictive diet), physical activity (aside from strenuous exercise limitation for 24 hours prior to and days 1-2 of each study phase) and nicotine use throughout study.
  • Willing to abstain from dietary supplements (e.g., metabolism boosters, appetite suppressants, weight loss aids) impacting appetite or metabolism (as determined by study PI) throughout the study.
  • Eats 3 meals per day at least 5 days/wk

Exclusion

  • Pregnant or lactating.
  • Taking prescription medications, other than a contraceptive, known to affect appetite, digestion and/or metabolism (e.g., anti-diabetic agents) (unless approved by study PI)
  • Any chronic medical condition that limits food intake or alters metabolism, appetite or digestive physiology (e.g., gastric bypass, gastrointestinal disease, dysphagia, diabetes).
  • Allergies and intolerances (e.g. gluten, dairy, nuts), unwillingness or inability to eat provided foods and beverages.
  • Score of ≥13 on the restraint scale or ≥9 on the disinhibition scale of the Eating Inventory
  • Weight gain or loss of \>5 lbs in the 2 weeks prior to study participation.
  • Not willing or unable to adhere to all study procedures and restrictions.

Key Trial Info

Start Date :

July 5 2022

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

May 4 2023

Estimated Enrollment :

20 Patients enrolled

Trial Details

Trial ID

NCT05408390

Start Date

July 5 2022

End Date

May 4 2023

Last Update

August 24 2023

Active Locations (1)

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1

US Army Research Institute of Environmental Medicine

Natick, Massachusetts, United States, 01760