Status:

COMPLETED

A Phase 1, Two-part, Randomized Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of a Liquid Formulation of Tricaprilin and Matching Placebo in Healthy Subjects

Lead Sponsor:

Cerecin

Conditions:

Alzheimer Disease

Eligibility:

All Genders

18-55 years

Phase:

PHASE1

Brief Summary

The purpose of this study is to evaluate the PK, safety, and tolerability of a new liquid formulation of tricaprilin.

Eligibility Criteria

Inclusion

  • Main
  • Healthy males and non-pregnant, non-lactating healthy females aged 18 to 55 years inclusive at time of signing informed consent with a body weight ≥55 kg.
  • Body mass index (BMI) 18.0 to 32.0 kg/m2 as measured at screening or, if outside the range, considered not clinically significant by the investigator.
  • Main

Exclusion

  • Serious adverse reaction or serious hypersensitivity to any drug or formulation excipients
  • Subjects with a history of fainting, dizziness, bradycardia or hypotension as considered clinically significant by the investigator
  • Subject has a medical condition that may adversely affect taste or smell activity

Key Trial Info

Start Date :

July 14 2022

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

October 24 2022

Estimated Enrollment :

45 Patients enrolled

Trial Details

Trial ID

NCT05408780

Start Date

July 14 2022

End Date

October 24 2022

Last Update

October 17 2023

Active Locations (1)

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Page 1 of 1 (1 locations)

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Quotient Sciences Miami

Miami, Florida, United States, 33126

A Phase 1, Two-part, Randomized Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of a Liquid Formulation of Tricaprilin and Matching Placebo in Healthy Subjects | DecenTrialz