Status:

COMPLETED

Effect of Opioid-free Anesthesia on PostOperative Nausea and Vomiting in Patients Undergoing Video-assisted Thoracoscopic Surgery

Lead Sponsor:

Beijing Chao Yang Hospital

Conditions:

Postoperative Nausea and Vomiting

Opioid Use

Eligibility:

All Genders

18-65 years

Phase:

NA

Brief Summary

This study aimed to verify whether an Opioid-free Anesthesia (OFA) could effectively reduce the incidence of PONV after thoracoscopic-assisted surgery compared with standard general anesthesia (OA) re...

Detailed Description

Postoperative Nausea and Vomiting (PONV) is one of the most common complications after general anesthesia, which significantly reduces postoperative comfort and satisfaction of patients perioperativel...

Eligibility Criteria

Inclusion

  • Inpatients planning elective thoracoscopic lobectomy or wedge resection under general anesthesia

Exclusion

  • ASA classification \> 4
  • BMI\>35kg/m2
  • Unable to communicate before surgery
  • Received radiation therapy, chemotherapy, opioids or hormonal drugs within 14 days before surgery
  • Anticipated intolerance to the anesthesia protocol of this study
  • Expect prolonged mechanical ventilation after surgery
  • Decline

Key Trial Info

Start Date :

June 7 2022

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

November 30 2024

Estimated Enrollment :

168 Patients enrolled

Trial Details

Trial ID

NCT05411159

Start Date

June 7 2022

End Date

November 30 2024

Last Update

March 19 2025

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Beijing Chaoyang Hospital

Beijing, Beijing Municipality, China, 100020