Status:
COMPLETED
A Study to Learn How the Study Medicine Called PF-07275315 Works in Healthy People
Lead Sponsor:
Pfizer
Conditions:
Healthy Volunteers
Eligibility:
All Genders
18-65 years
Phase:
PHASE1
Brief Summary
The purpose of this clinical trial is to learn about the safety and effects of the study medicine (called PF-07275315) in healthy participants. This study is seeking participants who: * Are healthy ...
Detailed Description
This is an first-in-human within-cohort randomized, participant- and investigator-blind, sponsor-open, placebo-controlled study of the safety, tolerability, PK, and PD following single and multiple es...
Eligibility Criteria
Inclusion
- This study is seeking participants who:
- Are overtly healthy as determined by medical evaluation.
- Are willing and able to comply with all scheduled visits, treatment plan, laboratory tests, lifestyle considerations, and other study procedures.
- Have a body mass index (BMI) of 17.5 to 32 kg/m2; and a total body weight \>50 kg (110 lb).
- This study is not seeking participants who have:
- Evidence of active, latent, or inadequately treated infection with Mycobacterium tuberculosis (TB) as defined by both of the following
- History of human immunodeficiency virus (HIV) infection, hepatitis B, or hepatitis C;
- Any of the following acute or chronic infections or infection history
- Any malignancies or have a history of malignancies with the exception of adequately treated or excised non-metastatic basal cell or squamous cell cancer of the skin, or cervical carcinoma in situ.
- Have undergone significant trauma or major surgery within 1 month of the first dose of study drug.
Exclusion
Key Trial Info
Start Date :
June 9 2022
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 13 2024
Estimated Enrollment :
65 Patients enrolled
Trial Details
Trial ID
NCT05411588
Start Date
June 9 2022
End Date
May 13 2024
Last Update
May 25 2025
Active Locations (5)
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1
Orange County Research Center
Lake Forest, California, United States, 92630
2
Orange County Research Center
Tustin, California, United States, 92780
3
New Haven Clinical Research Unit
New Haven, Connecticut, United States, 06511
4
Qps-Mra, Llc
South Miami, Florida, United States, 33143