Status:

COMPLETED

Feasibility Study of Novel Prescription Digital Therapeutic Supporting Unobserved Buprenorphine Initiation & Adherence

Lead Sponsor:

Pear Therapeutics, Inc.

Collaborating Sponsors:

Kaiser Foundation Research Institute

Whitman-Walker Institute, Inc.

Conditions:

Opioid Use Disorder

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The purpose of this study is to assess feasibility of an at-home digital therapy designed to support buprenorphine initiation and adherence.

Detailed Description

The purpose of this study is to develop and evaluate the acceptability of a novel feature for use with the prescription digital therapeutic reSET-O. This feature aims to improve the quality of treatm...

Eligibility Criteria

Inclusion

  • Provide written informed consent prior to any study specific assessments being performed
  • Male or female ≥18 years of age, inclusive
  • English proficiency to meaningfully participate in consent process, assessment and intervention
  • Meets clinical sites criteria for buprenorphine initiation (e.g. current opioid use)
  • Currently receiving buprenorphine outpatient treatment for OUD (Part 1) or wishing to start buprenorphine treatment
  • Capable of using common software applications on an internet-enabled mobile device (smart phone or tablet)
  • Interested in testing or using PEAR-002b
  • No prior history of reSET-O use
  • Has not participated in any other investigational drug trials within the past 30 days (or within 5 half-lives of study drug, whichever is longer) of enrollment
  • Is considered appropriate for participation by their clinician

Exclusion

  • Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) diagnosis of OUD and on methadone or naltrexone pharmacotherapy
  • DSM-5 diagnosis of OUD and already on buprenorphine
  • Planning to move out of the geographic area within 2 months
  • Unable to use English to participate in the consent process, the interventions, or assessments
  • Inability to comply with study procedures, due to severe medical conditions or otherwise
  • Currently receiving inpatient treatment for OUD
  • Women who are pregnant

Key Trial Info

Start Date :

November 4 2022

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 16 2022

Estimated Enrollment :

7 Patients enrolled

Trial Details

Trial ID

NCT05412966

Start Date

November 4 2022

End Date

December 16 2022

Last Update

January 9 2023

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Hassman Research Institute, LLC

Berlin, New Jersey, United States, 08009