Status:
COMPLETED
Aggregate Metabolic Phenotypes for (Poly)Phenols: Development of an Oral (Poly)Phenol Challenge Test (OPCT)
Lead Sponsor:
University of Parma
Collaborating Sponsors:
Azienda Ospedaliero-Universitaria di Parma
University of Birmingham
Conditions:
Individual Variability in (Poly)Phenol Metabolism
Cardiometabolic Health
Eligibility:
All Genders
18-74 years
Phase:
NA
Brief Summary
The study is a single-dose acute clinical trial aiming at identifying aggregate metabolic phenotypes for the main dietary (poly)phenols and assessing the factors associated with their formation. The ...
Eligibility Criteria
Inclusion
- Adult (18-74 y)
- BMI 18.5-35 kg/m\^2
Exclusion
- Past cardiovascular events and metabolic diseases including diabetes
- Inflammatory bowel diseases or gastro-intestinal surgery
- Renal (GFR\<60 ml/min) or hepatic diseases (liver enzymes \>2.5 fold higher)
- Immunodeficiency or autoimmune diseases (other than well-compensated hypothyroidism)
- Mental disorders
- Antibiotic therapy within the last month
- Food allergies
- Pregnancy or lactation
Key Trial Info
Start Date :
May 31 2022
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 26 2023
Estimated Enrollment :
300 Patients enrolled
Trial Details
Trial ID
NCT05414084
Start Date
May 31 2022
End Date
May 26 2023
Last Update
April 27 2025
Active Locations (2)
Enter a location and click search to find clinical trials sorted by distance.
1
University of Parma - Plesso Biotecnologico Integrato
Parma, PR, Italy, 43125
2
Azienda Ospedaliero-Universitaria di Parma
Parma, PR, Italy, 43126