Status:
UNKNOWN
The Association of Gut Microbes and Their Metabolites With Post-stroke Depression
Lead Sponsor:
The Affiliated Hospital of Xuzhou Medical University
Conditions:
Acute Ischemic Stroke
Eligibility:
All Genders
18+ years
Brief Summary
In this study, the clinical data of patients with AIS were collected, 16s RNA was used to detect the composition and diversity of intestinal flora, and flow cytometry and mass spectrometry were used t...
Detailed Description
In recent years, more and more studies have been conducted on the gut-brain axis, and gut microbes can affect the brain by regulating immune responses, metabolites, and neurotransmitters. The composit...
Eligibility Criteria
Inclusion
- Patients who suffered from acute ischemic stroke
- Within 7 days of the onset
- Signing the informed consent, willing and able to attend all study visits
Exclusion
- Severe aphasia，dysarthria, hearing loss，cognitive and consciousness impairment and unable to cooperate
- Previous diagnosis of depression or other mental disorder or who had recently accepted antidepressants or antipsychotics
- Gastrointestinal disease, and pregnant or lactating women
- Serious systemic diseases including malignant tumors
- Any antibiotics, probiotics or prebiotic treatment within 1 months
Key Trial Info
Start Date :
June 6 2022
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
May 31 2023
Estimated Enrollment :
200 Patients enrolled
Trial Details
Trial ID
NCT05414227
Start Date
June 6 2022
End Date
May 31 2023
Last Update
June 10 2022
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
The Affiliated Hospital of Xuzhou Medical University
Xuzhou, Jiangsu, China, 221002