Status:
RECRUITING
Combination of Artificial Intelligence and Mucosal Exposure Device to Enhance Colorectal Neoplasia Detection
Lead Sponsor:
Chinese University of Hong Kong
Collaborating Sponsors:
University Hospital Augsburg
Changi General Hospital
Conditions:
Adenoma
Colorectal Cancer
Eligibility:
All Genders
45-85 years
Phase:
NA
Brief Summary
The investigators hypothesize that the combined use of CADe system (ENDOAID) and mucosal exposure device (Endocuff Vision®) would improve the adenoma detection rate when compared to CADe system alone.
Detailed Description
High polyp miss rates were reported in standard colonoscopies. As a result, a significant proportion of interval CRC was attributed to the missed lesions during index colonoscopy. Risk factors of miss...
Eligibility Criteria
Inclusion
- Aged 45-85 years old;
- They require elective colonoscopy for colorectal cancer screening, polyp surveillance, or investigation of symptoms such as anemia or altered bowel habit;
- Written informed consent obtained.
Exclusion
- Contraindication to colonoscopy (e.g. intestinal obstruction or perforation)
- Contraindication or conditions precluding polyp resection (e.g. active gastrointestinal bleeding, uninterrupted anticoagulation or dual antiplatelets)
- Staged procedure for polypectomy or biopsy of known unresected lesions
- Previous surgical resection of colon
- Personal history of colorectal cancer
- Personal history of familial polyposis syndrome
- Personal history of inflammatory bowel disease
- Advanced comorbid conditions (defined as American Society of Anesthesiologists grade 4 or above)
- Pregnancy
- Unable to obtain informed consent
Key Trial Info
Start Date :
March 7 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2025
Estimated Enrollment :
1726 Patients enrolled
Trial Details
Trial ID
NCT05414448
Start Date
March 7 2023
End Date
December 31 2025
Last Update
May 17 2024
Active Locations (1)
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1
Prince of Wales Hospital
Shatin, Hong Kong Island, Hong Kong