Status:

COMPLETED

The Effects of Low Flow and Normal Flow Desflurane Anesthesia

Lead Sponsor:

Yuzuncu Yil University

Conditions:

Anesthesia

Liver Functions

Eligibility:

All Genders

65-100 years

Phase:

NA

Brief Summary

Aging is a physiological process. In the elderly, loss of functional reserve in all organ system, regression in anabolic processes and increase in catabolic processes are observed s (1). The number of...

Detailed Description

This prospective, randomized-controlled, observational study was approved by the ethics committee of Van Yuzuncu Yıl University (Date: 16.04.2021, Decision no: 05-27). The study was performed accordin...

Eligibility Criteria

Inclusion

  • Patients with an American Society of Anesthesiologists (ASA) status of class I-III,
  • Aged between 65 and 100 years,
  • Scheduled to undergo general anesthesia and, the surgeries that will take longer than 1 hour.

Exclusion

  • ASA class ≥ III patients
  • Thorasic surgery
  • Neurosurgery
  • Cardiorespiratory disease,
  • Uncontrolled diabetes mellitus,
  • Coagulation disorders,
  • Preoperative liver and renal dysfunction,
  • History of malignant hyperthermia,
  • Using nephrotoxic or hepatotoxic drugs,
  • Major bleeding (\>1000 cc) is predicted in the operation,
  • Chronic alcoholism,
  • Patients with drug use or withdrawal symptoms

Key Trial Info

Start Date :

May 28 2021

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

March 30 2022

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT05414721

Start Date

May 28 2021

End Date

March 30 2022

Last Update

June 10 2022

Active Locations (1)

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1

Van Yüzüncü Yıl University, Faculty of Medicine

Van, Tusba, Turkey (Türkiye), 65080