Status:

UNKNOWN

Taurine Supplementation Associated or Not With Exercise: Effect on Browning of White Adipose Tissue in Elderly Women With Sarcopenic Obesity

Lead Sponsor:

University of Sao Paulo

Conditions:

Browning of Subcutaneous White Adipose Tissue Post Intervention

Metabolic and Inflammatory Variables Post Intervention

Eligibility:

FEMALE

60-75 years

Phase:

NA

Brief Summary

The aging process is followed by metabolic and body composition changes, increasing the risk of obesity and sarcopenia. The coexistence of these conditions acts synergistically on each other and is kn...

Detailed Description

The aging process is followed by metabolic and body composition changes, increasing the risk of obesity and sarcopenia. The coexistence of these conditions acts synergistically on each other and is kn...

Eligibility Criteria

Inclusion

  • BMI between 30 and 40kg/m²;
  • Appendicular lean mass below 15 kg;
  • Dynamometry below the cutoff point adjusted for sex and BMI (less than or equal to 21kg);
  • "Sit and stand" test below the cut-off point adjusted for the age group, considering the number of repetitions in 30 seconds;
  • Present medical certificate to perform physical exercise

Exclusion

  • alcoholics
  • smokers
  • diseases that prevents the practice of physical activity
  • medical impediment to the practice of physical exercise throughout the study
  • infectious diseases
  • coronary diseases
  • chronic kidney diseases
  • undergoing nutritional monitoring or weight loss treatment
  • score ≤13 for cognitive screening on the Mini-Mental State Examination (MMSE)

Key Trial Info

Start Date :

February 27 2023

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 1 2024

Estimated Enrollment :

40 Patients enrolled

Trial Details

Trial ID

NCT05415176

Start Date

February 27 2023

End Date

June 1 2024

Last Update

November 29 2023

Active Locations (1)

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Escola de Educação Física e Esporte de Ribeirão Preto

Ribeirão Preto, São Paulo, Brazil, 14040-907