Status:
RECRUITING
Embolization for Meningioma
Lead Sponsor:
St. Olavs Hospital
Conditions:
Meningioma
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The natural course for meningioma suggests that a majority will grow over time. Treatment is usually indicated in growing or symptomatic meningiomas. Surgery is usually primary treatment, but there is...
Eligibility Criteria
Inclusion
- Radiological diagnose of typical intracranial meningioma (homogenous contrast enhancement or dural attachment)
- Indication for treatment due to growth, symptoms or both
- Tumor location suggestive of vascular supply via middle meningeal artery branches
- Age 18 years or older
- Karnofsky performance status of 90 or better (able to carry on normal activity and work)
Exclusion
- Informed consent not possible (e.g. language barriers, aphasia, cognitive impaired)
- Previously treated for meningioma
- Intraosseous growth
- Tumor related brain edema
- Neurofibromatosis type 2
- Systemic cancer
- Epilepsy
- Progressive neurodegenerative disorder (eg. MS, Parkinsons disease)
- History of psychiatric disorder
- Unfit for participation for any other reason judged by the physician including patients
- Contraindications to MRI
- Allergic to contrast agents
- Relative contraindications to endovascular treatment judged from CT angiography (tortoise carotid arteries, carotid stenosis, calcified aortic arch, anatomical vascular variants/anomalies suggesting increased risk with endovascular treatment)
- DSA (Digital subtraction angiography) from carotid artery suggesting that significant vascular supply is from other vessels than the MMA.
Key Trial Info
Start Date :
October 10 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
August 1 2037
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT05416567
Start Date
October 10 2022
End Date
August 1 2037
Last Update
June 5 2025
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
St Olavs Hospital
Trondheim, Norway, 7006