Status:

COMPLETED

Arthrometry and Clinical Tests for Diagnosing ACL Tears

Lead Sponsor:

Liverpool University Hospitals NHS Foundation Trust

Conditions:

Anterior Cruciate Ligament Injuries

Anterior Cruciate Ligament Rupture

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Anterior cruciate ligament (ACL) tears are diagnosed by combining the patient's history and physical examination but clinical tests (e.g., Lachman, anterior drawer, and pivot shift) are less accurate ...

Detailed Description

Approximately 40-50% of patients that present with immediate knee swelling (within 2 hours) following injury have an anterior cruciate ligament (ACL) tear. Potential consequences of an ACL tear includ...

Eligibility Criteria

Inclusion

  • History of knee injury (\<3 weeks since trauma for the validity study) with immediate swelling (\<2 hours) but no fracture on X-ray.
  • Participant is willing and able to give informed consent for participation in the study.
  • Male or Female, aged 18 years or above.
  • No contraindications to arthrometer testing or MRI (see exclusion criteria).
  • Healthy contralateral knee; no current or previous history of significant knee injury, or a history of previous minor injury that is symptomatic at the time of recruitment. No previous knee surgery.

Exclusion

  • The participant may not enter the study if they are unable to provide written consent to study participation, or there are contraindications to arthrometer testing or MRI, including the following:
  • History of chronic disease or disorder that may put the participants at risk because of participation in the study including non-united fractures, severe peripheral vascular disease, aneurysms, recent (\<3 months) radiotherapy or chemotherapy, neurological disorders (e.g., Parkinson's disease), skin conditions at point of testing, severe osteoporosis, malignancy, rheumatoid arthritis.
  • Patients with implanted surgical clips or other ferromagnetic material including shrapnel, metallic implants (excluding joint replacements \>6 weeks since surgery), non-MRI compatible prosthetic heart valves, surgery within 6 weeks, pregnancy, patients with compromised thermoregulatory systems.
  • History of chronic musculoskeletal disease or disorder in either leg.

Key Trial Info

Start Date :

February 6 2023

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

July 1 2024

Estimated Enrollment :

102 Patients enrolled

Trial Details

Trial ID

NCT05416632

Start Date

February 6 2023

End Date

July 1 2024

Last Update

November 13 2024

Active Locations (2)

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Page 1 of 1 (2 locations)

1

Liverpool University Hospitals Nhs Foundation Trust

Liverpool, Merseyside, United Kingdom, L7 8XP

2

Aintree University Hospital NHS Foundation Trust

Liverpool, Merseyside, United Kingdom, L9 7AL