Status:

COMPLETED

Clinical Value of Metagenomic Sequencing in Neonatal Sepsis

Lead Sponsor:

Children's Hospital of Fudan University

Collaborating Sponsors:

Quanzhou Women's and Children's Hospital

Shengjing Hospital

Conditions:

Neonatal Sepsis

Eligibility:

All Genders

Up to 28 years

Brief Summary

This study aimed to enroll 2000 neonatal patients with suspected sepsis or clinical diagnosed sepsis. These patients will undergo both conventional methods and metagenomics sequencing to detect the pa...

Detailed Description

Infectious diseases remain leading causes of mortality and morbidity in children. Rapid and accurate diagnosis of infectious diseases in children is important for developing an effective treatment and...

Eligibility Criteria

Inclusion

  • Neonates with suspected early-onset sepsis or late-onset sepsis;
  • Neonates diagnosed with clinical sepsis.

Exclusion

  • Died before the results of conventional methods test or metagenomics test were obtained;
  • Suffering from diseases of the blood system;
  • Suffering from malignant tumor;
  • Birth defects, congenital heart disease or autoimmune disease.

Key Trial Info

Start Date :

April 1 2022

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

December 30 2022

Estimated Enrollment :

200 Patients enrolled

Trial Details

Trial ID

NCT05416918

Start Date

April 1 2022

End Date

December 30 2022

Last Update

December 28 2023

Active Locations (1)

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1

Children Hospital of Fudan University

Shanghai, China, 201102