Status:
COMPLETED
Glycogen and Appetite
Lead Sponsor:
University of Bath
Conditions:
Energy Intake
Eligibility:
All Genders
18-60 years
Phase:
NA
Brief Summary
Obesity is the outcome of chronic excessive energy intake and reduced energy expenditure leading to energy imbalance. It is a risk factor for many preventable diseases such as metabolic disease and it...
Eligibility Criteria
Inclusion
- Males aged 18-60 and premenopausal women
- Physically active (at least 30 minutes of exercise 3 times a week)
- Body mass index 18.0-30.0 kg·m-2
Exclusion
- Weight instability (\>5kg change in body mass over last 6 months)
- Restrained eater (e.g. limiting food intake, calorie counting)
- Current smoker
- Aversion or allergy to test meal foods
- Pregnant or lactating
- Amenorrhoea in women
- Any medical condition or medication that could introduce bias into the study (e.g., diabetes, CVD, lipid or glucose metabolism altering medications)
- Any cardiopulmonary condition prohibiting exercise testing
- Any contraindication to niacin or aspirin (e.g., diabetes, gout, clotting disorders, allergy to non-steroidal anti-inflammatory drugs)
Key Trial Info
Start Date :
October 10 2022
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 30 2024
Estimated Enrollment :
15 Patients enrolled
Trial Details
Trial ID
NCT05417659
Start Date
October 10 2022
End Date
August 30 2024
Last Update
March 27 2025
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Department for Health, University of Bath
Bath, United Kingdom, BA2 7AY