Status:

COMPLETED

Interest of Nitazoxanide Treatment of Enterocytozoon Bieneusi Intestinal Microsporidiosis

Lead Sponsor:

University Hospital, Clermont-Ferrand

Conditions:

Microsporidiosis Intestinal

Eligibility:

All Genders

18+ years

Brief Summary

Microsporidia are pathogenic fungi mainly responsible for profuse watery diarrhea, requiring management in immunocompromised patients. The main immunocompromised population affected by these infection...

Eligibility Criteria

Inclusion

  • With a diagnosis of intestinal infection caused by E. bieneusi between 01/01/2018 and 03/31/2022
  • having received treatment with nitazoxanide ("NITAZO" group), or fumagillin ("FUMA" group), or albendazole ("ABZ") or having received no specific treatment but having benefited from an adjustment of the doses of immunosuppressants ("IS" group)

Exclusion

  • With a diagnosis of extraintestinal infection
  • With a diagnosis of infection by a species other than E. bieneusi

Key Trial Info

Start Date :

April 1 2022

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

June 1 2022

Estimated Enrollment :

80 Patients enrolled

Trial Details

Trial ID

NCT05417815

Start Date

April 1 2022

End Date

June 1 2022

Last Update

July 27 2022

Active Locations (24)

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Page 1 of 6 (24 locations)

1

CHU Amiens

Amiens, France

2

CHU Besançon

Besançon, France

3

CHU Bordeaux

Bordeaux, France

4

CHU Brest

Brest, France