Status:
UNKNOWN
Effect of Different Color Lights on the Internal Clock and Alertness in Humans
Lead Sponsor:
University of Basel
Collaborating Sponsors:
Horizon 2020 - European Commission
Conditions:
Light Flashing
Eligibility:
All Genders
18-35 years
Phase:
NA
Brief Summary
The main aim of this study is to investigate the effects of cone-modulated light emitted from a visual display on human circadian physiology and cognitive performance in the evening.
Detailed Description
The investigators will generate single/multiple cone-isolating contrasts with equivalent stimuli for other cones and melanopsin photoreceptors. The investigators will assess melatonin suppression unde...
Eligibility Criteria
Inclusion
- Age: 18 - 35 years
- Sex: male or female normal color vision, male dichromat (i.e. tested by CCT, HRR, Farnsworth Munsell 100 Hue Test)
- BMI: 18.5 - 29.9 self-reported weight and height (i.e. normal and overweight according to WHO)
- Signed consent form of participants
- Chronotype: Morningness-Eveningness Questionnaire (31 - 69)
- Sleep Quality: Pittsburgh Sleep Quality Index, PSQI (≤5)
Exclusion
- High myopia (\> -6 diopters)
- High hyperopia (\< +6 diopters)
- Transmeridian travel (\>2 time zones) \<1 month prior to the first session of the study
- Shift work \<3 months prior to the beginning of the study
- Ophthalmological or optometric conditions (cataract, glaucoma, retinal detachment, macular conditions, chronic inflammations, eye injuries, or operations)
- General health concerns or disorders, including heart and cardiovascular, neurological, nephrological, endocrinological, and psychiatric conditions
- Medication impacting on visual, neuroendocrine, sleep, and circadian physiology
- For females only: pregnancy, use of hormonal contraceptives, lactation or breastfeeding
- Drug (urinary drug screening) and alcohol use
- Non-compliance with sleep-wake times: \>1 deviation from ±30 minute window sleep and wake-up time
- Extreme chronotype (Munich Chronotype Questionnaire \<2 or \>7)
- Current participation in other clinical trials
- Exclusion criteria due to study requirements:
- Inability to understand and/or follow study materials or procedures
- Insufficient knowledge of project language
Key Trial Info
Start Date :
June 20 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
September 15 2023
Estimated Enrollment :
68 Patients enrolled
Trial Details
Trial ID
NCT05423002
Start Date
June 20 2022
End Date
September 15 2023
Last Update
June 21 2022
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Centre for Chronobiology
Basel, Switzerland, 4002