Status:
RECRUITING
Speckle Tracking Echocardiography as a Tool for Early Diagnosis of Impaired Fetal Growth Twin Pregnancies
Lead Sponsor:
University Hospital, Ghent
Collaborating Sponsors:
KU Leuven
Maxima Medical Center
Conditions:
Fetal Growth Restriction
Cardiac Remodeling, Ventricular
Eligibility:
FEMALE
18-45 years
Brief Summary
In this project there are 2 time points during the pregnancy included, namely at 21 weeks and 30 weeks of gestation, to measure the predictive values of FGR, strain and strain rate. The fetal growth p...
Detailed Description
Fetal growth restriction (FGR) is diagnosed in 5-10% of the pregnancies. After preterm birth, it is the second leading cause of perinatal morbidity and mortality. Twin pregnancies have a higher occurr...
Eligibility Criteria
Inclusion
- Singleton or dichorionic twin pregnancy
- Pregnant women 21 weeks ( ± 2 weeks) of gestation at the first visit
- Women ≥ 18 years
Exclusion
- Women pregnant of multiples of higher order (≥3 siblings) Monochorionic twin pregnancy
- Fetal arrhythmia
- Known fetal congenital or genetic abnormalities
- Any suspicion of congenital fetal anomalies that might influence fetal cardiac function
- Pre-existing maternal hypertensive disease
- Autoimmune disease including systemic lupus erythematosus
- History of stillbirth
- Diabetes mellitus (mother)
Key Trial Info
Start Date :
June 22 2023
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
February 1 2028
Estimated Enrollment :
360 Patients enrolled
Trial Details
Trial ID
NCT05423665
Start Date
June 22 2023
End Date
February 1 2028
Last Update
September 26 2023
Active Locations (3)
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1
Ghent University Hospital
Ghent, Belgium, 9000
2
Universitair ziekenhuis Leuven
Leuven, Belgium, 3000
3
Maxima medical center
Eindhoven, Netherlands, 5631