Status:
COMPLETED
Dietary Fiber and Gut Microbiome Study
Lead Sponsor:
Center of Food and Fermentation Technologies
Conditions:
Healthy
Eligibility:
All Genders
20-60 years
Phase:
NA
Brief Summary
The purpose of this dietary intervention is to study the effects of several dietary fibers on the gut microbiota at the personal level. Hypothesis 1: Intake of specific dietary fibers improves the blo...
Detailed Description
The study design is a cross-over, pre-post intervention trial. All participants are enrolled into all study periods. Study consists of baseline period, four periods of dietary fiber intervention and f...
Eligibility Criteria
Inclusion
- Age 20-60
- Normal bowel function
- Omnivorous diet
- Ability to provide a signed written informed consent
- Willing to provide stool and blood specimens over the 22-week study period
Exclusion
- Diagnosed history of chronic diseases including coronary heart disease, stroke, cancer, type 1 or 2 diabetes mellitus, inflammatory bowel disease, gastritis, autoimmune disease, or rheumatoid arthritis
- Medication: statins, blood pressure medications, antidepressants, other prescription medications
- History of bariatric operation, removal of the gallbladder.
- Food allergies, lactose intolerance
- Recent (previous 3 months) use of antibiotics
- Intake of highly dosed pre- or probiotics 2 weeks prior and during the study
- Current pregnancy or breastfeeding
- Volunteers showing previously unrecognized illness will also be excluded
- Individual unable to give informed consent
Key Trial Info
Start Date :
February 1 2022
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 31 2022
Estimated Enrollment :
15 Patients enrolled
Trial Details
Trial ID
NCT05424640
Start Date
February 1 2022
End Date
July 31 2022
Last Update
February 8 2023
Active Locations (1)
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1
Center of Food and Fermentation Technologies
Tallinn, Harju, Estonia, 12618