Status:
RECRUITING
Intravenous vs Oral Acetaminophen in Postoperative Hip Fracture Adult Patients
Lead Sponsor:
University Health Network, Toronto
Conditions:
Hip-fracture
Surgery
Eligibility:
All Genders
60+ years
Phase:
PHASE4
Brief Summary
The INTACT-HIP trial study will evaluate feasibility of conducting a randomized, double-blinded controlled trial comparing postoperative treatment with intravenous (IV) acetaminophen versus oral aceta...
Eligibility Criteria
Inclusion
- 60 years of age and older
- Patients who were ambulating without human assistance before fracture, with any type of non-neoplastic hip fracture
- Patients undergoing surgical treatment as an inpatient
Exclusion
- Patients with neoplastic hip fracture
- Severe cognitive impairment (Montreal Cognitive Assessment (MoCA) \<10)
- Pre-existing delirium
- Known hypersensitivity or allergy to acetaminophen
- Severe or chronic liver or kidney dysfunction
- Planned postoperative ventilation
- Swallowing issues and/or dysphagia
- English language limitation
- Weight \<50kg
Key Trial Info
Start Date :
January 23 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 30 2026
Estimated Enrollment :
42 Patients enrolled
Trial Details
Trial ID
NCT05425355
Start Date
January 23 2023
End Date
June 30 2026
Last Update
May 30 2025
Active Locations (1)
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1
Toronto Western Hospital (UHN)
Toronto, Ontario, Canada, M5T 2S8