Status:
UNKNOWN
Remote Ischemic Conditioning for the Treatment of Resistant Hypertension
Lead Sponsor:
Ji Xunming,MD,PhD
Conditions:
Resistant Hypertension
Eligibility:
All Genders
30-80 years
Phase:
NA
Brief Summary
This study aims to explore the efficacy and safety of remote ischemia adaptation for the treatment of resistant hypertension.
Detailed Description
Resistant hypertension is defined as a blood pressure of 140/90 mmHg or higher despite adherence to at least three antihypertensive drugs (including one diuretic), accounting for 20% to 30% of patient...
Eligibility Criteria
Inclusion
- Aged 30\~80 years old;
- Taking ≥ 3 antihypertensive drugs (including one diuretic) for more than 4 weeks regularly;
- Office blood pressure ≥ 140/90mmhg, and 24 h average blood pressure ≥ 130/80 mmHg;
- Willing to participate in the study, follow the study protocol, and provide informed consent.
Exclusion
- Secondary hypertension;
- eGFR\<45ml/min/1.73m2；
- Office blood pressure ≥180/110 mmHg, and 24 h average blood pressure ≥ 170/100 mmHg；
- Hypertensive crisis occurred within 3 months;
- Type 1 diabetes;
- Cardiovascular events occurred within 3 months;
- Atrial fibrillation;
- Presence of any severe disease that adversely affects the subject or study;
- Patients with contraindication for remote ischemic conditioning, such as vascular injury, soft tissue injury, orthopedic injury, or arm infection;
- Pregnancy, lactation, or planned pregnancy;
- Patients not suitable for this trial considered by researchers for other reasons；
- Participation in another device or drug trial simultaneously.
Key Trial Info
Start Date :
October 1 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
March 30 2023
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT05426707
Start Date
October 1 2022
End Date
March 30 2023
Last Update
September 8 2022
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