Status:
COMPLETED
Effect of Microbiome Modulation by Diet in Functional Constipation
Lead Sponsor:
Istanbul Medipol University Hospital
Conditions:
Constipation - Functional
Eligibility:
All Genders
20-65 years
Phase:
NA
Brief Summary
Current medications and behavioral modifications have limited success in the treatment of functional constipation (FC). An individualized diet based on microbiome analysis may improve symptoms in FC. ...
Eligibility Criteria
Inclusion
- Patients fulfilling Rome IV criteria for functional constipation (FC)
- Patients who had a colonoscopy performed within the last 5 years
- Patients who had a colonic transit time assessment within the last 3 months
- Patients who had a magnetic resonance defecography within the last 3 months
Exclusion
- Use of antibiotics, probiotics, and/or prebiotics within the last 4 weeks
- Gastrointestinal endoscopy within the last 4 weeks
- Major gastrointestinal surgery (total/segmental gastrectomy, small bowel and/or colonic resection)
- Cholecystectomy
- Inflammatory bowel diseases
- Celiac disease
- Any etiology of chronic constipation other than FC (irritable bowel syndrome, rectocele, dyssynergic defecation, opioid use)
- Endocrine, metabolic or neurologic disorders causing constipation (hypothyroidism, Parkinson's disease, paraplegia)
Key Trial Info
Start Date :
December 14 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 27 2021
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT05429333
Start Date
December 14 2020
End Date
December 27 2021
Last Update
June 23 2022
Active Locations (1)
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1
Medipol University Esenler Hospital
Istanbul, Other (Non U.s.), Turkey (Türkiye), 34230