Status:

COMPLETED

Safety & PK of Single Doses of MT1980

Lead Sponsor:

Monument Therapeutics Limited

Collaborating Sponsors:

ICON plc

Conditions:

Neuroinflammatory Response

Eligibility:

All Genders

18-65 years

Phase:

PHASE1

Brief Summary

MT1980 is being developed as a treatment for neuroinflammation (an inflammatory response in the brain and/or spinal cord). Much research has focused on the central role of neuroinflammation in the pat...

Eligibility Criteria

Inclusion

  • Healthy volunteers with good physical and mental health
  • Body Mass Index 18 to 30 kg/m2
  • Men \& women of child-bearing potential must agree to use adequate contraception
  • Willing \& able to provide written informed consent and to communicate and participate in the study

Exclusion

  • Clinically significant abnormal biochemistry, haematology, urinalysis results
  • Results of screening liver function or kidney function tests outside of normal ranges
  • Heavy daily smoking or use of nicotine containing substances

Key Trial Info

Start Date :

June 1 2022

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

October 4 2022

Estimated Enrollment :

24 Patients enrolled

Trial Details

Trial ID

NCT05429840

Start Date

June 1 2022

End Date

October 4 2022

Last Update

November 2 2022

Active Locations (1)

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1

Icon Early Development Services

Groningen, Netherlands