Status:

COMPLETED

The Effects of Nicardipine and Esmolol Applied for Controlled Hypotension

Lead Sponsor:

Yuzuncu Yil University

Conditions:

Hypotension

Surgery-Complications

Eligibility:

All Genders

18-60 years

Phase:

NA

Brief Summary

In this study, the effects of nicardipine and esmolol applied for controlled hypotension in rhinoplasty on hemodynamics and regional renal oxygenation will be investigated.

Detailed Description

The procedure to be applied to the cases to be included in the study: Patients randomized by the sealed envelope method will be divided into 2 groups (40 patients in each group). The sealed envelope...

Eligibility Criteria

Inclusion

  • Between 18-60 years of age,
  • ASA I-II,
  • undergoing elective rhinoplasty surgery,
  • it was decided to apply controlled hypotension,
  • BMI (body mass index) between 18-25 kg/m2,
  • informed about the subject and
  • patients with written consent

Exclusion

  • ASA III-IV patients,
  • hypertension disease,
  • using anticoagulant medication,
  • pregnancy,
  • kidney failure,
  • bleeding diathesis,
  • active infection,
  • allergy to drugs to be used,
  • BMI≥30,
  • refusing to participate in the study,
  • hypothermic,
  • patients taking antibiotics, anticonvulsants, antiarrhythmics, cholinesterase inhibitors

Key Trial Info

Start Date :

May 12 2022

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

August 30 2022

Estimated Enrollment :

80 Patients enrolled

Trial Details

Trial ID

NCT05430724

Start Date

May 12 2022

End Date

August 30 2022

Last Update

September 27 2022

Active Locations (1)

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Van yuzuncu Yıl University, Dursun Odabas Medical Center

Van, Turkey (Türkiye), 65080