Status:
UNKNOWN
Efficacy Of Doxycycline & Versus Rifampin In Treatment Of Rhinoscleroma
Lead Sponsor:
Assiut University
Conditions:
Rhinoscleroma
Eligibility:
All Genders
18-70 years
Phase:
PHASE1
Brief Summary
The study is conducted To evaluate the Efficacy of Doxycycline (alone and in combination with Ciprofloxacin) as an alternative to the regular regimen in treating rhinoscleroma, especially for cases wi...
Detailed Description
Rhinoscleroma is a chronic granulomatous disease endemic in many eastern countries including Egypt, Its causative agent is a gram-negative bacillus, Klebsiella rhinoscleromatis. Low socioeconomic popu...
Eligibility Criteria
Inclusion
- Patients will be included after confirmation by histopathological examination.
- Patients presented in active stages of the disease.
- Patients between 18-70 years.
Exclusion
- Any granulomatous lesion or features suggestive of rhinoscleroma associated with any other nasal lesions like syphilis, leprosy and tuberculosis were excluded.
- Patients below 18 years and above 70 years.
- Biopsy-negative cases.
- Patients in Atrophic or Sclerotic Stages of the disease.
Key Trial Info
Start Date :
August 21 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
July 31 2023
Estimated Enrollment :
45 Patients enrolled
Trial Details
Trial ID
NCT05431673
Start Date
August 21 2022
End Date
July 31 2023
Last Update
July 7 2022
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