Status:
UNKNOWN
Transversus Abdominis Plane Blocks With and Without Dexamethasone
Lead Sponsor:
University of Saskatchewan
Conditions:
Colorectal Disorders
Regional Anesthesia Morbidity
Eligibility:
All Genders
18+ years
Phase:
PHASE1
PHASE2
Brief Summary
Dexamethasone will be used as an adjunct to local anesthetics (bupivacaine) to prolong the duration of laparoscopically-placed transversus-abdominis plane blocks in elective colorectal resection.
Detailed Description
Advances in minimally invasive surgery have reduced postoperative morbidity and enhanced recovery. Despite increased use of minimally invasive techniques, postoperative pain remains a challenging aspe...
Eligibility Criteria
Inclusion
- age \> 18
- ASA class I-III
- elective or urgent inpatient laparoscopic/laparoscopic assisted colorectal surgery.
Exclusion
- emergency surgery
- open surgery
- contraindications to laparoscopic surgery (ie. adhesions, inability to tolerate pneumoperitoneum)
- ASA class 4
- age \< 18
- pregnant or breastfeeding women
- significant cardiorespiratory/hepatic/renal disease
- allergy to any study drugs
- inability to consent
- inability to respond to pain assessments
- inability to use the patient-controlled analgesia device (PCA)
- preoperative chronic opioid use
Key Trial Info
Start Date :
September 1 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
August 31 2024
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT05432934
Start Date
September 1 2022
End Date
August 31 2024
Last Update
December 7 2023
Active Locations (1)
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1
Royal University Hospital
Saskatoon, Saskatchewan, Canada, S7N 0W8