Status:

COMPLETED

Non-invasive Ventilation in Patients With Cardiac Heart Failure

Lead Sponsor:

University of Gran Rosario

Conditions:

Heart Failure

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Patients with heart failure (HF) have a reduced exercise tolerance as the main result of the disease. This exercise intolerance is due to heart conditions, but also to dysfunction of the respiratory a...

Detailed Description

The main objective is to evaluate whether the use of NIV during Constant Treadmill Load Tests (CTLT) enhances exercise performance in Cardiac Heart Failure (CHF) patients on a treadmill. Each recruit...

Eligibility Criteria

Inclusion

  • Ejection fraction demonstrated by echocardiography ≤ 40% (in the last 12 months).
  • NYHA functional class I - III.
  • Clinical stability, defined as four weeks prior to the start of the study without hospitalizations.
  • Signed informed consent.
  • ≥ 18 years of age.

Exclusion

  • Chronic obstructive pulmonary disease (COPD), unstable angina or significant arrhythmias.
  • Myocardial infarction in the last 3 months, primary valve disease and anemia (hemoglobin under 13 g/dl for men or 12 g/dl for women).
  • Patients who are smokers or ex-smokers of less than one year.
  • Patients with cognitive impairment that prevents the correct understanding of the evaluations.
  • Any neuromuscular or osteoarticular condition that limits test performance.
  • Refusal to participate.

Key Trial Info

Start Date :

June 28 2022

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 5 2022

Estimated Enrollment :

12 Patients enrolled

Trial Details

Trial ID

NCT05433610

Start Date

June 28 2022

End Date

December 5 2022

Last Update

December 15 2022

Active Locations (1)

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University of Gran Rosario

Rosario, Santa Fe Province, Argentina, 2000

Non-invasive Ventilation in Patients With Cardiac Heart Failure | DecenTrialz