Status:
UNKNOWN
Microbiota and Immunoassay in Women With and Without Endometriosis: a Pilot Study
Lead Sponsor:
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Conditions:
Endometriosis
Endometriosis-related Pain
Eligibility:
FEMALE
18-45 years
Phase:
NA
Brief Summary
Endometriosis is an estrogen-dependent chronic inflammatory disease characterized by the presence of endometrial tissue outside the uterine cavity. This pathology has a prevalence of about 5-10% in re...
Eligibility Criteria
Inclusion
- BMI \<30 kg / m2
- no hormonal therapy (estrogen-progestin, progestogen, GnRH analogues) in progress for at least 1 month
- the endometriosis group include women who will undergo surgery for endometriosis. The control group include women who will undergo surgery for other gynecological indications (i.e .: abdominal surgical emergencies, tubal infertility, non-endometriotic ovarian cysts) in which the presence of endometriosis will be excluded during the surgery.
Exclusion
- hormonal therapy in progress (estrogen-progestins, progestins, GnRH analogues)
- antibiotic and / or probiotic therapy in the 8 weeks before the samples
- pregnancy
- menopausal state
- BMI ≥ 30 kg / m2
- presence of active systemic diseases, neoplasms, positive clinical history for autoimmune diseases, active vaginosis or positive history for pelvic inflammatory disease
Key Trial Info
Start Date :
April 9 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
November 30 2023
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT05433909
Start Date
April 9 2022
End Date
November 30 2023
Last Update
May 23 2023
Active Locations (1)
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1
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Milan, Italy, 20122