Status:
RECRUITING
Preoperative Corticosteroids in Autoimmune Thyroid Disease
Lead Sponsor:
Indiana University
Conditions:
Graves Disease
Hashimoto Disease
Eligibility:
All Genders
18+ years
Phase:
PHASE4
Brief Summary
This study proposes to randomize patients about to undergo surgery for their autoimmune, inflammatory thyroid disease, and determine if a short course of corticosteroids decreases the inflammation of ...
Eligibility Criteria
Inclusion
- ■ Graves' disease or Hashimoto's disease with positive thyroid autoantibodies (TgAb, TPO, TSI, and/or TRAb) undergoing total thyroidectomy for their disease.
Exclusion
- Pediatric patients \< 18
- Prior treatment with RAI
- Prior neck surgeries
- Known diagnosis of thyroid cancer
- Diabetic patients on medications
- A history of adverse reactions to corticosteroids.
- Patients on any immunosuppressive regimen (such as organ transplant patients or patients treated for other autoimmune conditions). This includes patients with recent history of steroid therapy, or a history of adverse reactions to corticosteroids.
Key Trial Info
Start Date :
June 16 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 30 2026
Estimated Enrollment :
76 Patients enrolled
Trial Details
Trial ID
NCT05435547
Start Date
June 16 2023
End Date
December 30 2026
Last Update
May 1 2025
Active Locations (3)
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1
IU Health North Hospital
Indianapolis, Indiana, United States, 46032
2
IU Health Methodist Hospital
Indianapolis, Indiana, United States, 46202
3
IU Health University Hospital
Indianapolis, Indiana, United States, 46202