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Status:

COMPLETED

Outcome of Preserved Mitral Valve Apparatus During Mitral Valve Replacement

Lead Sponsor:

Suez Canal University

Collaborating Sponsors:

National Research Centre, Egypt

Conditions:

Diseases of Mitral Valves

Abnormality of Mitral Valve Annulus (Disorder)

Eligibility:

All Genders

30-65 years

Phase:

NA

Brief Summary

Are there differences in outcome of mitral valve replacement with preservation of mitral apparatus among rheumatic and/or ischemic mitral lesions?. Mitral valve replacement with preservation of leafl...

Detailed Description

Objectives: The aim is to compare outcome of modified preservation of mitral valve apparatus during prosthetic mitral replacement for rheumatic versus myocardial ischemia \&mitral valve disease. Meth...

Eligibility Criteria

Inclusion

  • Inclusion Criteria::
  • Mitral stenosis (MS)
  • symptoms are severely limiting and cannot be managed with diuresis and heart rate control.
  • Mitral regurgitation(MR):
  • \* acute severe MR require surgical correction for hemo-dynamics and relief of symptoms .
  • Chronic primary mitral regurgitation:
  • \* rheumatic heart disease: replacement before irreversible changes occur can be curative.
  • Mixed Mitral Stenosis and Mitral Regurgitation:
  • If beta blockers and diuretics do not relieve symptoms, replacement should be performed only in patients who have severe limiting symptoms.
  • Myocardial ischemia associating or complicated with miral valve disease.
  • Exclusion criteria
  • Patients showing good response to medical therapy, and Cases complicated by:
  • ineffective endocarditis,
  • previous myocardial re-vascularization
  • ischemic ventricular septal defect,
  • left ventricular aneurysm,
  • Ruptured papillary muscles of mitral apparatus.

Exclusion

    Key Trial Info

    Start Date :

    December 28 2016

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ACTUAL

    End Date :

    December 28 2021

    Estimated Enrollment :

    100 Patients enrolled

    Trial Details

    Trial ID

    NCT05438433

    Start Date

    December 28 2016

    End Date

    December 28 2021

    Last Update

    June 30 2022

    Active Locations (2)

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    Page 1 of 1 (2 locations)

    1

    Suez Canal University

    Ismailia, Egypt, +064

    2

    Suez Canal University

    Ismailia, Egypt, 002-064