Status:
COMPLETED
Intrathecal Morphine Versus Morphine-dexmedetomidine Combination for Postoperative Pain Control After Total Knee Replacement
Lead Sponsor:
Tanta University
Conditions:
Intrathecal Morphine
Intrathecal Morphine-dexmedetomidine Combination
Eligibility:
All Genders
50-65 years
Phase:
NA
Brief Summary
Total knee replacement is one of the most painful orthopedic surgical procedures. Patients who undergo total knee replacement are usually older and have limited cardiac and pulmonary reserves. The inc...
Detailed Description
105 patients, aged \>50 years, with ASA Physical Status Class II and III, scheduled for TKR under spinal anesthesia will be included in this study. 105 Patients will be randomly allocated into three ...
Eligibility Criteria
Inclusion
- 105 patients, aged \>50 years, with ASA Physical Status Class II and III, scheduled for TKR under spinal anesthesia
Exclusion
- Patients who had bleeding disorders
- Patients who had heart, liver, or renal failure
- Patients who had systemic infections or infections of their injection sites
- Patients with a known allergy to study
- Patients who had 2nd or 3rd-degree heart block
- Those with low back pain or other back problems
- History of drug or alcohol abuse
- Body mass index (BMI) \> 30 kg\\m2
- Patients with psychiatric illnesses that would interfere with perception and assessment of pain.
Key Trial Info
Start Date :
July 1 2022
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 30 2023
Estimated Enrollment :
105 Patients enrolled
Trial Details
Trial ID
NCT05439564
Start Date
July 1 2022
End Date
January 30 2023
Last Update
November 24 2023
Active Locations (1)
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1
Faculty of Medicine, Tantan University Hospital
Tanta, Egypt