Status:
COMPLETED
Impact of Cottonseed Oil on Oxidative Stress, Inflammation, and Metabolism
Lead Sponsor:
Montana State University
Conditions:
Inflammation
Healthy
Eligibility:
All Genders
18-55 years
Phase:
NA
Brief Summary
Recent research evidence suggests that cottonseed oil (CSO) may have both direct and indirect anti-inflammatory and anti-oxidative impacts linked to bioactive components of CSO and favorable alteratio...
Detailed Description
The approach will be to enroll a population of healthy individuals (n=32) in a four-armed (30 g CSO, 30 g OO, 60 g CSO, and 60 g OO), randomized, double-blind, parallel controlled trial to compare the...
Eligibility Criteria
Inclusion
- are between the ages of 18-55 years
- have body mass index between 18-27 kg/m2
Exclusion
- take medications to lower cholesterol, lipids, and/or inflammation,
- take blood pressure medications,
- take antioxidant supplements (Vitamin E or C or iron) at levels greater than 800 IU/day,
- have diabetes, a gallbladder condition, or have had gallbladder removed,
- take oral contraceptives regularly,
- have smoked in the past 30 days,
- consume alcohol more than 14 drinks/week,
- have an allergy to dairy, egg, tree nuts, peanuts, shellfish, soy, fish, wheat, legumes, extra virgin olive oil, and cottonseed oil, or have been on a ketogenic or paleo diet in the past six weeks,
- pregnant or lactating,
- on weight loss diet or planning to change exercise regimen,
- have physical mobility issues or are not able to walk on a treadmill,
- or have other health concerns or conditions that may interfere with your participation in the study
Key Trial Info
Start Date :
August 8 2022
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 3 2023
Estimated Enrollment :
47 Patients enrolled
Trial Details
Trial ID
NCT05439590
Start Date
August 8 2022
End Date
November 3 2023
Last Update
November 18 2023
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Nutrition Research Laboratory
Bozeman, Montana, United States, 59717