Status:
COMPLETED
Stimulating Compassion UsingTranscutaneous Vagus Nerve Stimulation
Lead Sponsor:
University College, London
Conditions:
Healthy Volunteers
Eligibility:
All Genders
18-35 years
Phase:
NA
Brief Summary
This experimental proof-of-concept study in healthy volunteers investigates whether a specific form of self-relating, namely, self-compassion, can be controlled through non-invasive stimulation of the...
Detailed Description
The role of the vagus nerve in regulating cardiac, respiratory, and gut functioning via brainstem nuclei is well-established. More recently, its role has been examined in relation to the modulation of...
Eligibility Criteria
Inclusion
- Fluency in English
- Good (including corrected) vision and hearing.
Exclusion
- Current use of any medication for a psychiatric condition
- Regular use of any medication used to treat a cardiovascular condition or inflammation
- Use of any illicit recreational drug \>2/week
- Regularly consuming \>14 standard UK 'units' of alcohol
- Currently receiving treatment for any mental health condition
- Scores on screening measures of depression (PHQ-2) and/or anxiety (GAD-2) that indicate significant levels of current/recent anxiety or depression (scores on either \>4)
- History of serious mental health problems (schizophrenia, bipolar disorder)
- Past or current cardiovascular or neurological problems
- Current/past problems related to chronic/recurring facial or ear pain
- Skin irritation/ broken skin at stimulation site
- Pregnancy or likelihood of becoming pregnant during study
- Previous adverse response to meditation.
Key Trial Info
Start Date :
June 27 2022
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 15 2023
Estimated Enrollment :
120 Patients enrolled
Trial Details
Trial ID
NCT05441774
Start Date
June 27 2022
End Date
March 15 2023
Last Update
May 23 2023
Active Locations (1)
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1
Clinical Psychopharmacology Unit
London, United Kingdom, WC1E 6BT