Status:

RECRUITING

Further Evaluation of Safety and Performance of the NEXUS Aortic Arch Stent Graft System and the Custom-Made NEXUS Multibranch™ Aortic Arch Stent Graft System

Lead Sponsor:

Endospan Ltd.

Conditions:

AAT9

Eligibility:

All Genders

18+ years

Brief Summary

The goal of this observational study is to collect clinical information on how safe, and how well the NEXUS Aortic Arch Stent Graft System and the Custom-Made NEXUS DUO™ Aortic Arch Stent Graft System...

Eligibility Criteria

Inclusion

  • Male and female age ≥18 years
  • The subject is indicated for implant of the NEXUS Aortic Arch System in accordance with the current IFU, or
  • The subject is indicated for implant of the custom-made NEXUS DUO Aortic Arch System in accordance with the current IFU, or
  • The subject has been already implanted, after February 2019, with the NEXUS or the NEXUS DUO according to the relevant IFU
  • The subject is able and willing to provide informed consent to participate in the study.
  • Subject is not currently enrolled in another investigational study or registry that would directly interfere with the current study, except if the subject is participating in a mandatory government registry, or a purely observational registry with no associated treatments. Each instance should be brought to the attention of the sponsor to determine eligibility.
  • In the opinion of the Investigator, life expectancy exceeds one year
  • The subject is not pregnant or planning to become pregnant.
  • In the physician's opinion, subject's renal function is stable for the NEXUS procedure.
  • In the opinion of the investigator, subject does not have co-morbidities or planned surgeries that will interfere with the implant of the device, e.g., major cardiac surgery or interventional procedure in the last 90 days, MI or cerebral vascular accident (CVA) in the last 90 days

Exclusion

    Key Trial Info

    Start Date :

    November 9 2022

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ESTIMATED

    End Date :

    July 1 2030

    Estimated Enrollment :

    70 Patients enrolled

    Trial Details

    Trial ID

    NCT05636527

    Start Date

    November 9 2022

    End Date

    July 1 2030

    Last Update

    December 4 2025

    Active Locations (18)

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    Page 1 of 5 (18 locations)

    1

    Cliniques universitaires Saint Luc

    Brussels, Belgium, 1200

    2

    UZ Leuven

    Leuven, Belgium, 3000

    3

    Aretaieio Hospital

    Nicosia, Cyprus, Cyprus, 2024

    4

    APHP Henri Mondor

    Paris, France