Status:
UNKNOWN
Effect of Quadratus Lumborum Block With Compound Lidocaine and Esketamine on Pain After Colorectal Surgery
Lead Sponsor:
Tianjin Medical University General Hospital
Conditions:
Postoperative Pain
Eligibility:
All Genders
20-65 years
Phase:
NA
Brief Summary
Purpose: To explore effects of ultrasound-guided quadratus lumborum block with compound lidocaine and esketamine on postoperative pain after colorectal surgery.
Detailed Description
Poor post-surgical pain control is a leading factor that hinders the physicalrehabilitation, and causes acute cognitive impairment and chronic painsyndrome. Recently, the multimodal analgesia strategi...
Eligibility Criteria
Inclusion
- Subject is scheduled to undergo colorectal cancer surgery under general anesthesia
- Subject's American Society of Anesthesiologists physical status is I-III.
- The subject's parent/legally authorized guardian has given written informed consent to participate
Exclusion
- Subject has a diagnosis of bronchial asthma, coronary heart disease, severe hypertension, renal failure or liver failure.
- Subject has a diagnosis of Insulin dependent diabetes.
- Subject is allergy and contraindication to local anesthetics or any components of local anesthetics.
- Subject has a history of chronic pain, a history of alcohol or opioid abuse, pre- existing therapy with opioids, intake of any analgesic drug within 48 hours before surgery.
- Subject has any contraindication for the use of patient-controlled analgesia (PCA).
- Subject is pregnant or breast-feeding.
- Subject is obese (body mass index \>30kg/m\^2).
- Subject is incapacity to comprehend pain assessment and cognitive assessment.
Key Trial Info
Start Date :
August 6 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
February 15 2024
Estimated Enrollment :
160 Patients enrolled
Trial Details
Trial ID
NCT05964985
Start Date
August 6 2023
End Date
February 15 2024
Last Update
July 28 2023
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