Status:

RECRUITING

Sodium Accumulation Study in Haemodialysis: Brain Study

Lead Sponsor:

University Hospitals of Derby and Burton NHS Foundation Trust

Collaborating Sponsors:

University of Nottingham

Conditions:

Dialysis; Complications

Eligibility:

All Genders

50-75 years

Brief Summary

The aim of the research study is to look at a new type of MRI scanning that can measure the amount of sodium in different parts of the body. Sodium (or 'salt') levels are very important in maintaining...

Detailed Description

Haemodialysis (HD) sustains life in patients with end-stage kidney disease (ESKD) but is associated with a marked increase in cognitive impairment, being three times more common and presenting at a yo...

Eligibility Criteria

Inclusion

  • Age 50-75 years inclusive
  • Male and female patients with CKD stage 5 receiving chronic haemodialysis
  • Patient has been dialysis dependent for at least 3 months
  • Must be able to follow simple instruction in English (on safety ground for MRI scans) and be able to understand the nature and requirements of the study

Exclusion

  • Active infection or malignancy
  • Amputee
  • Pregnancy
  • Contraindication to MRI scanning including claustrophobia, pacemaker, metallic implants etc
  • Unable or unwilling to provide informed consent
  • Medical conditions or overall physical frailty precludes scan session in opinion of investigator
  • Any condition which could interfere with the patient's ability to comply with the study

Key Trial Info

Start Date :

July 18 2024

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

February 1 2025

Estimated Enrollment :

10 Patients enrolled

Trial Details

Trial ID

NCT05966116

Start Date

July 18 2024

End Date

February 1 2025

Last Update

August 9 2024

Active Locations (1)

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Centre for Kidney Research and Innovation

Derby, United Kingdom, DE22 3NE