Status:

ACTIVE_NOT_RECRUITING

Trial to Increase FEP Attendance

Lead Sponsor:

University of Pennsylvania

Collaborating Sponsors:

Penn Innovation in Suicide Prevention for Implementation Research (INSPIRE) Center

Conditions:

First-Episode Psychosis

Eligibility:

All Genders

18+ years

Phase:

EARLY_PHASE1

Brief Summary

Individuals with first-episode psychosis (FEP) are at high-risk for several poor functional and clinical outcomes, including suicide. Coordinated Specialty Care (CSC) is a multidisciplinary, team-base...

Eligibility Criteria

Inclusion

  • For all participants, age ≥ 18 years old.
  • For intervention trial and patient feasibility and acceptability measurement: Patients with first-episode psychosis, enrolled in Coordinated Specialty Care at the Psychosis Education, Assessment, Care and Empowerment (PEACE) clinic and Psychosis Evaluation and Recovery Center (PERC).
  • For clinician feasibility and acceptability measurement at intervention sites: Clinicians working at PEACE and PERC where the intervention will be piloted.
  • For clinician implementation facilitator and barrier assessment at other Connection LHS sites to assess for scalability: Clinicians in Connection LHS who work at sites other than PEACE and PERC.Participants must sign the informed consent form

Exclusion

  • For intervention trial and patient feasibility and acceptability measurement: Expectation of leaving coordinated specialty care programing within 6 months (which will exclude all of the PI's patient panel) and/or intellectual disability of sufficient degree that the patient's primary psychiatrist expects to compromise capacity to consent to this research and/or psychosis secondary to another medical condition (which may not share the same motivational features that are otherwise understood about the primary psychiatric conditions with psychosis).
  • For clinician feasibility and acceptability measurement at intervention sites: Study investigators who work at these clinics will be excluded from participation in the feasibility and acceptability study component given their role in the trial planning and execution.
  • For clinician implementation facilitator and barrier assessment at other Connection LHS sites to assess for scalability: none.

Key Trial Info

Start Date :

February 1 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

January 31 2026

Estimated Enrollment :

145 Patients enrolled

Trial Details

Trial ID

NCT05967195

Start Date

February 1 2025

End Date

January 31 2026

Last Update

December 12 2025

Active Locations (3)

Enter a location and click search to find clinical trials sorted by distance.

Page 1 of 1 (3 locations)

1

University of North Carolina at Chapel Hill (ENCOMPASS Program)

Raleigh, North Carolina, United States, 27608

2

PEACE Program, Horizon House, Inc.

Philadelphia, Pennsylvania, United States, 19123

3

University of Pennsylvania

Philadephia, Pennsylvania, United States, 19104