Status:

COMPLETED

Correlation Between Serum Uric Acid and Pulmonary Hypertension in Obstructive Sleep Apnea Syndrome

Lead Sponsor:

Alexandria University

Conditions:

Obstructive Sleep Apnea

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

This study aimed to correlate serum uric acid levels and PAH in OSAHS patients.

Detailed Description

Obstructive sleep apnea-hypopnea syndrome is the most common form of SRBDs. Recurrent hypoxia, that accompanies OSAHS increases the degradation of ATP, which in turn increase uric acid concentration t...

Eligibility Criteria

Inclusion

  • Clinical diagnosis of OSAHS by overnight polysomnography (AHI ≥ 5/ hr)
  • ≥18 years old.

Exclusion

  • Other sleep disorders as narcolepsy or hypersomnia were excluded as well as Patients with neuropsychiatric disorders.
  • Hemodynamically unstable patients
  • Patients with other chronic respiratory or cardiac diseases
  • Patients with other known causes of pulmonary hypertension
  • Patients with any disease or on medication that could alter excretion or urinary metabolism of uric acid such as Excessive uric acid production

Key Trial Info

Start Date :

January 1 2018

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 1 2020

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT05967754

Start Date

January 1 2018

End Date

December 1 2020

Last Update

August 1 2023

Active Locations (1)

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1

Rania Ahmad Sweed

Alexandria, Egypt, 000000