Status:
UNKNOWN
A Bidirectional Study in Exploring the Dynamic Changes of Plasma and Urine Metabolites of Head and Neck Cancer
Lead Sponsor:
Nanfang Hospital, Southern Medical University
Conditions:
Head and Neck Cancer
Metabolite
Eligibility:
All Genders
18-75 years
Brief Summary
Dynamic changes in the internal environment of the body are important clues for early detection, diagnosis and even cure of head and neck tumors. This project uses the combination of proteomics techno...
Detailed Description
Head and neck cancer is the seventh most common malignant tumor in the world, and China is a country with a high incidence of head and neck cancer. Dynamic changes in the internal environment of the b...
Eligibility Criteria
Inclusion
- Head and neck cancer patients
- Age 18-75 years old;
- Male or non-pregnant female;
- Patients who were normatively diagnosed as head and neck tumors according to the WHO standards of 2017;
- The general situation is good: KPS score ≥70;
- No other malignant tumors.
- Healthy people
- Age 18-75 years old;
- Male or non-pregnant female;
- No history of head and neck related diseases or other diseases known to affect blood lipid/protein metabolism.
Exclusion
- Previous history of non-research related head and neck conditions or other known effects on blood metabolism (except for controlled type 2 diabetes);
- With a history of other malignancies (except cell carcinoma and cervical carcinoma in situ);
- Diseases that require long-term use of immunosuppressive drugs (including steroids), including but not limited to congenital or acquired immunodeficiency disorders or active central nervous system rotations, metastatic cancer, active infection, or uncontrolled heart disease;
- Concurrent with other uncontrolled serious medical conditions, such as unstable heart disease that requires treatment Disease, poorly controlled diabetes (fasting blood glucose \> 1.5× the upper limit of normal), mental illness and a history of severe allergies.
- BMI less than 18 or greater than 25.
Key Trial Info
Start Date :
March 25 2023
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
June 1 2025
Estimated Enrollment :
500 Patients enrolled
Trial Details
Trial ID
NCT05969262
Start Date
March 25 2023
End Date
June 1 2025
Last Update
August 3 2023
Active Locations (1)
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1
Southern medical university
Guangzhou, Guangdong, China, 510515