Status:
COMPLETED
Evaluation of Efficacy and Safety of Topical 1% Medroxyprogesterone in the Corneal Epithelium Healing After PRK
Lead Sponsor:
Isfahan University of Medical Sciences
Collaborating Sponsors:
Isfahan Ophthalmology Research Center
Conditions:
Photorefractive Keratectomy
Eligibility:
All Genders
18+ years
Phase:
PHASE2
PHASE3
Brief Summary
In this clinical trial, it is decided that 30 patients who are candidates for photorefractive keratectomy will receive a drop of prepared medroxyprogesterone randomly in one of their eyes, in addition...
Detailed Description
Patients who have referred for refractive surgery to correct myopia and myopia-stigmatism first undergo complete examinations that are required before the procedure, which includes the following exami...
Eligibility Criteria
Inclusion
- 1- Age above 18 years 2- Myopia and myopic astigmatism 3- The stability of the patient's refraction over the past year 4-- Not using contact lenses at least 3 weeks before the operation 5- Absence of history of KCN and any type of corneal ectasia in the patient himself or his first degree family 6- Full satisfaction and knowledge of patients to enter the plan 7- No history of previous eye surgery and eye trauma 8- Absence of active eye diseases, corneal dystrophy, retinal diseases, glaucoma, dry eyes of any degree.
- 9- Absence of systemic diseases that can potentially interfere with wound healing, including diabetes, vascular collagen diseases, and pregnancy.
- 10- Not taking inhaled or systemic steroids actively or within 3 months before the procedure
Exclusion
- The patient's lack of consent to continue the study
- Failure to visit the patient for follow-up
Key Trial Info
Start Date :
April 21 2023
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 6 2023
Estimated Enrollment :
74 Patients enrolled
Trial Details
Trial ID
NCT05973253
Start Date
April 21 2023
End Date
July 6 2023
Last Update
August 2 2023
Active Locations (2)
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1
Isfahan eyes research centre
Isfahan, Iran, 0098
2
Isfahan Eye Research Center
Isfahan, Iran, 81746-73461