Decentrialz logo
  • HIPAA Compliant
  • ISO 27001 Certified
Find Trials
About UsContact
Become a Volunteer+1 877 705 1914

Status:

RECRUITING

Blood Lipid Responses to Diet

Lead Sponsor:

University of Oxford

Conditions:

Nutritional and Metabolic Diseases

Eligibility:

All Genders

18-65 years

Phase:

NA

Brief Summary

The macronutrient composition of our diet (proportions of carbohydrates, fats and proteins) strongly influences the way our body stores and utilises substrates (e.g., fats and sugars), which in turn i...

Detailed Description

Dietary and lifestyle interventions are central to lowering the risk and preventing the development of metabolic disease, including non-alcoholic fatty liver disease, type 2 diabetes, and cardiovascul...

Eligibility Criteria

Inclusion

  • Participant is willing and able to give informed consent for participation in the study.
  • Male or Female, aged ≥18 to ≤65 years
  • Body mass index (BMI) ≥19 to ≤35 kg/m2
  • No medical condition or relevant drug therapy that is known to affect the liver, adipose tissue, or cardiac metabolism.
  • Weight stable for the previous 3 months

Exclusion

  • Aged \<18 or \>65 years
  • BMI \<19 or \>35 kg/m2
  • A blood haemoglobin \<135 mg/dL for men and \<120 mg/dL for women
  • Donated (or lost) ≥250 mL of blood in the previous two months
  • On a weight loss diet or decreased their body weight by \>5% in the previous 3 months
  • Currently adhering to or have consumed in the previous 3 months a diet with a notably altered macro-nutrient content (e.g. high-fat - low-carbohydrate diet)
  • Have increased their body weight by \>5% in the previous 3 months
  • Any metabolic condition or relevant drug therapy
  • Current smoker
  • History of alcoholism or a greater than recommended alcohol intake (\>30 g of alcohol daily for men and \>20 g of alcohol daily for women)
  • History of albumin allergy.
  • Pregnant or nursing mothers
  • History of severe claustrophobia

Key Trial Info

Start Date :

February 15 2023

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

January 1 2028

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT05973539

Start Date

February 15 2023

End Date

January 1 2028

Last Update

December 27 2023

Active Locations (2)

Enter a location and click search to find clinical trials sorted by distance.

Page 1 of 1 (2 locations)

1

Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford

Oxford, United Kingdom, OX3 7LE

2

Oxford Centre for Diabetes, Endocrinology and Metabolism

Oxford, United Kingdom, OX3 7LE