Status:
COMPLETED
Mindfulness and Attention Training Intervention to Lower Distractibility in Aging
Lead Sponsor:
The University of Texas at Dallas
Conditions:
Healthy Aging
Eligibility:
All Genders
65-85 years
Phase:
NA
Brief Summary
The goal of this interventional study is to test the efficacy of combined mindfulness meditation training and cognitive training on brain function and cognition in healthy older adults. Participants w...
Detailed Description
Nearly 14 million people are projected to develop Alzheimer's disease (AD) by 2050 in the USA alone, with those affected by mild cognitive impairment (MCI) being especially at risk. Therefore, interve...
Eligibility Criteria
Inclusion
- right-handed
- aged 65 to 85 years old
- at least high school education
- learned English before age 5.
- screening cognitive assessment (MoCA) score above the threshold
- physical and sensory capacity sufficient to undertake an fMRI study:
- the ability to stay still for the duration of the scan
- sufficient finger dexterity to press buttons on the provided button boxes during the scan
- vision acuity of at least 20/30 after correction
- no color blindness
- no claustrophobia
- no metal implants above the waist
- if female, cannot be pregnant or likely to be pregnant.
- cannot have participated in similar training in the past two years.
Exclusion
- left-handed or ambidextrous
- weigh over 300 lb
- did not attain at least high school education
- have not learned English before the age of 5
- screening cognitive assessment (MoCA) score below the threshold
- color blind
- have vision acuity worse than 20/30 after correction
- experience of excessive hand tremor or other motor impairment related to hand movement
- history of cardiovascular disease other than treated hypertension
- diabetes
- psychiatric disorders
- illness or trauma affecting the central nervous system, including stroke and head trauma resulting in loss of consciousness over 5 seconds
- substance/alcohol abuse
- use of medication with anti-depressant, anti-psychotic effects (use of hypnotic medication is allowed only occasionally at bedtime).
- certain medical devices or implants
- non-medical sources of metal, e.g., shrapnel, prior hobby/work with metal
- MRI image revealing evidence of pathology
- female participants that are pregnant or likely to become pregnant
- participated in similar training in the past two years
Key Trial Info
Start Date :
March 17 2022
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 27 2024
Estimated Enrollment :
16 Patients enrolled
Trial Details
Trial ID
NCT05974605
Start Date
March 17 2022
End Date
June 27 2024
Last Update
December 3 2024
Active Locations (1)
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1
Center for Vital Longevity
Dallas, Texas, United States, 75235