Status:

COMPLETED

Role of Propolis Endodontic Irrigant on Post-Operative Pain

Lead Sponsor:

Dow University of Health Sciences

Conditions:

Post-operative Pain

Symptomatic Irreversible Pulpitis

Eligibility:

All Genders

18-60 years

Phase:

PHASE3

Brief Summary

The goal of this clinical trial is to compare propolis and sodium hypochlorite as endodontic irrigants in patients presenting with symptomatic irreversible pulpitis. . The main question it aims to an...

Detailed Description

Sodium hypochlorite as an endodontic irrigant, poses problems of toxicity. Additionally, its unfavorable odor, taste, failure to remove the smear layer, and proteolytic effect have deleterious effects...

Eligibility Criteria

Inclusion

  • ASA-I and II individuals who are between the ages of 18 and 60 years.
  • Patients with mandibular and maxillary premolars who have been diagnosed with symptomatic irreversible pulpitis (with either a normal periapex or symptomatic apical periodontitis).
  • Patients who score moderate to severe (4-10) on a preoperative visual analogue scale (VAS=1-10)

Exclusion

  • Patients suffering from severe pain because of traumatic occlusion.
  • Teeth with extensive damage, calcified canals, periapical radiolucency, root resorption, and an open apex.
  • Patients with compromised medical condition (ASA-III and above)
  • Patients who are unable to communicate effectively in either Urdu or English.
  • Pregnant and lactating ladies
  • Patients who are allergic to honey or bee pollen.

Key Trial Info

Start Date :

April 1 2023

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

August 15 2023

Estimated Enrollment :

44 Patients enrolled

Trial Details

Trial ID

NCT05974748

Start Date

April 1 2023

End Date

August 15 2023

Last Update

September 7 2023

Active Locations (1)

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Dow International Dental College

Karachi, Sindh, Pakistan, 75500