Status:
UNKNOWN
Reduction Of Dietary Salt Intake To Control Systolic Blood Pressure In Hypertensive Older Patients
Lead Sponsor:
Mario Negri Institute for Pharmacological Research
Conditions:
Hypertension
Eligibility:
All Genders
60+ years
Phase:
NA
Brief Summary
REPRESS is an open label, pragmatic, multicenter, randomized controlled phase III trial with blinded endpoint with 1:1 (intervention to control arm) allocation ratio. The REPRESS trial is aimed to de...
Eligibility Criteria
Inclusion
- Community-dwelling patients aged ≥60 years;
- Prescribed ≥3 drugs;
- A) Systolic blood pressure ≥130 and ≤160 mmHg for patients prescribed stable antihypertensive therapy (at least 1 drug (ATC code: C02\*, C03\*, C07\*, C08\*, C09\*)); B) Systolic blood pressure ≥140 and ≤160 mmHg for those patients not prescribed any antihypertensive drug;
- Capable of feeding independently;
- Own a smartphone;
- Frequently consuming home-cooked meals (≥4 days during a week and ≥3 during the weekend per month);
- Giving signed informed consent.
Exclusion
- Living in a nursing home or having applied for nursing home admission;
- Being prescribed (adding, switching or changing dosage) an antihypertensive drug in the three months before enrollment;
- Undergoing renal replacement therapy with dialysis or having renal impairment with estimated glomerular filtration rate (eGFR) \<25 mL/min/1.73 m2 (assessed by CKD-EPI formula) \[30\] within previous six months or at the screening assessment;
- Following a low-sodium dietary regimen;
- Being unable or refusing to sign informed consent.
Key Trial Info
Start Date :
October 1 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2025
Estimated Enrollment :
266 Patients enrolled
Trial Details
Trial ID
NCT05976477
Start Date
October 1 2023
End Date
December 31 2025
Last Update
September 1 2023
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