Status:

UNKNOWN

Characterization of Tissue Biochemical Composition in Gastric Precancerous/Cancerous Lesions

Lead Sponsor:

National University Hospital, Singapore

Collaborating Sponsors:

Endofotonics Pte Ltd

Conditions:

Gastric Cancer

Eligibility:

All Genders

21+ years

Phase:

NA

Brief Summary

This is a study intended to utilize endoscopic biopsies from gastric precancerous/ cancerous lesions and adjacent normal mucosa to characterize tissue biochemical composition changes as determined by ...

Detailed Description

This is a study intended to utilize endoscopic biopsies from gastric precancerous/ cancerous lesions and adjacent normal mucosa to characterize tissue biochemical composition changes as determined by ...

Eligibility Criteria

Inclusion

  • They are aged 21 years and above
  • They will be undergoing upper gastrointestinal endoscopy for any of the following:
  • Current or known history of gastric dysplasia and gastric cancer, or
  • Endoscopic surveillance after previous endoscopic or surgical resection for gastric dysplasia or gastric cancer.
  • They must be mentally competent.
  • They must be willing and able to comply with all study procedures.

Exclusion

  • Subjects with bleeding disorders, such as haemophilia, in whom biopsies are contraindicated.
  • Subjects with active bleeding or coagulopathy precluding biopsies.
  • Pregnant subjects.
  • The subject with severe co-morbid illness, such as end-stage renal failure (ESRF), congestive cardiac failure (CCF) and advanced liver cirrhosis.
  • Subjects with other severe acute or chronic medical or psychiatric condition or laboratory abnormality that may interfere with the interpretation of study results or would make the subject unsuitable for entry into the study

Key Trial Info

Start Date :

October 27 2022

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

March 31 2024

Estimated Enrollment :

25 Patients enrolled

Trial Details

Trial ID

NCT05977478

Start Date

October 27 2022

End Date

March 31 2024

Last Update

August 4 2023

Active Locations (1)

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1

National University Hospital

Singapore, Singapore