Status:

RECRUITING

Denervation for Osteoarthritis in the PIP-joint Efficacy Study (DOPS)

Lead Sponsor:

Karolinska Institutet

Collaborating Sponsors:

Stockholm South General Hospital

Conditions:

Osteoarthritis Finger

Surgery

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The goal of this clinical trial is to compare the effects of a surgical and a non-surgical treatment method in patients with osteoarthritis in the proximal interphalangeal (PIP) joint. The main questi...

Detailed Description

This is a parallel group, two-arm, randomized, controlled trial comparing the effects of surgical denevation to patient education plus exercise in patients with symptomatic PIP joint osteoarthritis. ...

Eligibility Criteria

Inclusion

  • Age ≥ 18 years.
  • Chronic symptomatic osteoarthritis in the PIP-joint.
  • Radiological signs of osteoarthritis on posteroanterior and lateral radiographs assessed by the Kellgren-Lawrence classification (grade II-IV) (Kellgren \& Lawrence, 1957).
  • Clinical signs of PIP-joint arthritis.

Exclusion

  • Inflammatory arthritis.
  • Ongoing infection in the hand.
  • Inability to co-operate with the follow-up protocol.
  • Intra-articular glucocorticoid, PRP or Hyaluronic acid injections in the affected joint less than 3 months prior to enrollment.

Key Trial Info

Start Date :

September 25 2023

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

July 15 2029

Estimated Enrollment :

90 Patients enrolled

Trial Details

Trial ID

NCT05980793

Start Date

September 25 2023

End Date

July 15 2029

Last Update

December 2 2024

Active Locations (1)

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1

Department of Hand Surgery, Södersjukhuset

Stockholm, Sweden