Status:
COMPLETED
Effects of Exogenous Ketosis on Renal Function, Renal Perfusion, and Sodium Excretory Capacity in Healthy Subjects
Lead Sponsor:
Gødstrup Hospital
Conditions:
Ketosis
Ketonemia
Eligibility:
All Genders
18-30 years
Phase:
NA
Brief Summary
This is a randomized, placebo-controlled, double-blinded crossover design. Fifteen healthy subjects will be randomized to receive either ketone bodies (KE4) or placebo delivered by KetoneAid. After a ...
Detailed Description
Background: Renewed interest in ketone bodies has emerged, partly driven by the recent success of selective sodium glucose co transporter 2 (SGLT-2) inhibition in preventing cardiovascular deaths in p...
Eligibility Criteria
Inclusion
- BMI \< 30 kg/m2
- Safe contraception if women in childbearing age
- Normal biochemical screening
Exclusion
- Pregnancy or breast feeding
- Major heart-, liver-, kidney-, lung-, neurological- or endocrine disease
- Daily use of prescription drugs (expect for contraceptives)
- Alcohol or drug abuse
- Periodic fasting
- Routinely intake of ketogenic diet
Key Trial Info
Start Date :
August 10 2023
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 11 2024
Estimated Enrollment :
16 Patients enrolled
Trial Details
Trial ID
NCT05980858
Start Date
August 10 2023
End Date
April 11 2024
Last Update
November 22 2024
Active Locations (1)
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1
The University Clinic of Nephrology and Hypertension
Herning, Jutland, Denmark, 7400