Status:
RECRUITING
Using Gut Microbial Gbu Gene Testing to Estimate Host TMAO Production Capacity
Lead Sponsor:
National Taiwan University Hospital
Conditions:
Gut Dysbiosis for TMAO Production From L-carnitine Consumption
Eligibility:
All Genders
18-70 years
Phase:
NA
Brief Summary
The risk of cardiovascular diseases from red meat consumption varies among individuals due to variations in gut microbiota. L-carnitine in red meat can be converted to TMAO in the body by certain bact...
Detailed Description
The risk of developing cardiovascular diseases due to the consumption of red meat varies among individuals, and this may be attributed to differences in the composition and function of gut microbiota....
Eligibility Criteria
Inclusion
- Adult with age between 18 to 70
- Must be able to swallow tablets
Exclusion
- Antibiotics use within one month
- L-carnitine supplement use within one month
- Chronic diarrhea
- Myasthenia gravis
- Diabetes mellitus
- Parathyroid disorders
- Chronic kidney disease
- Epilepsy
- Severe anemia
- Cardiovascular diseases.
Key Trial Info
Start Date :
July 24 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
July 30 2026
Estimated Enrollment :
230 Patients enrolled
Trial Details
Trial ID
NCT05980884
Start Date
July 24 2023
End Date
July 30 2026
Last Update
May 11 2025
Active Locations (1)
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1
National Taiwan University Hospital
Taipei, Taiwan