Status:

RECRUITING

Enhanced Recovery After Major Surgery and Chronic Pain for Total Knee Arthroplasty

Lead Sponsor:

Hospital for Special Surgery, New York

Conditions:

Chronic Pain

Opioid Use

Eligibility:

All Genders

18-75 years

Phase:

NA

Brief Summary

The goal of this interventional clinical trial is to assess opioid consumption 24-48 hrs post anesthesia block among patients undergoing total knee arthroplasty. The main question it aims to answer is...

Detailed Description

The purpose of this study is to see if adding a continuous ACB catheter will extend analgesia beyond the 24-48 hour period. This interventional clinical trial will assess opioid consumption in patient...

Eligibility Criteria

Inclusion

  • Patients with osteoarthritis scheduled for a primary total knee arthroplasty with a participating surgeon
  • Age 18 to 75 years
  • Planned use of regional anesthesia
  • Ability to follow study protocol
  • English speaking (secondary outcomes include questionnaires validated in English only)
  • Patients of participating surgeons: Drs. Mayman, Jerabek, Westrich, Su, Della Valle, Alexiades
  • Lives within one hour of the hospital
  • Has a smartphone

Exclusion

  • Hepatic or renal insufficiency
  • Younger than 18 years old and older than 65
  • Patients undergoing general anesthesia
  • Allergy or intolerance to one of the study medications
  • BMI \> 40
  • Diabetes
  • ASA of III,IV
  • Chronic gabapentin/pregabalin use (regular use for longer than 3 months)
  • PCS \> 30
  • Chronic opioid use (taking opioids for longer than 3 months, or daily oral morphine equivalent of \>5mg/day for one month)
  • Patients with severe valgus deformity or flexion contracture
  • Patients unable to follow home catheter instructions and unwilling to go home with an infusing catheter
  • Patients who have no home caregivers in the event if a catheter is to be sent home with the patient
  • Patients with planned stay at rehab facility

Key Trial Info

Start Date :

June 12 2023

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

January 1 2025

Estimated Enrollment :

64 Patients enrolled

Trial Details

Trial ID

NCT05981105

Start Date

June 12 2023

End Date

January 1 2025

Last Update

December 27 2024

Active Locations (1)

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Hospital for Special Surgery

New York, New York, United States, 10021